Description

Also known as Insulin Growth Factor 1 Long R3 IGF-1 LR3 is a single chain of polypeptides which consists of 83 amino acids. The growth factor IGF1 has many other effects which helps promoting growth and development in growth hormone. There is a long term analogy of IGF-1 human growth factor i.e. LR3, which is responsible for support of recombinant bio-pharmaceuticals manufacture at large.

Chemical Description of IGF LR3

Synonyms: Long R3 IGF-1, IGF-1 LR3 (Long R3 IGF-1), LR3 IGF, IGF1 LR3, Long Arg3 IGF-1

Chemical Composition of IGF 1 LR3

The actual composition of analogy of IGF-1(83 amino acid) i-e Polypeptide Long R3 Insulin-Like Growth Factor-1 (IGF1 LR3), is a complete sequence of IGF-1. Although at position 3, Arginine (Arg) substitutes the Glumetic Acid (Glu) along with an extension peptide of 13 amino acids. The effect of this sequence takes place in such a way that it prohibits protein binding in IGF-1 LR3 and thus allowing it 20 to 30 hours more half-life duration.

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IGF 1 LR3 Interactions

The behaviour of an active IGF differs in different types of tissues. It stimulates protein and associated cell components in muscle cells and as a result amino acid absorption occurs and protein synthesis increases. For adipose tissues, IGF-1 LR3 acts as energy source by mobilizing fat for using it as energy. It prohibits insulin from carrying glucose to cell membrane in lean tissues and furthermore making the cell to use and burn fat for energy production.

The promotional effect of IGF-1 LR3 in retention of nitrogen and protein synthesis builds new muscle tissues. Due to this effect, the muscles grow through both processes i.e. Hyperplasia &Mutagenesis. Hyperplasia. The first refers increase in the number of muscle cells & and the later represents actual growth of muscle fibres.